Bacterial invasion of host cells (E-Book, 2004) [WorldCat.org]
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Bacterial invasion of host cells
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Bacterial invasion of host cells

Autor: Richard J Lamont
Verlag: Cambridge ; New York : Cambridge University Press, 2004.
Serien: Advances in molecular and cellular microbiology, 5.
Ausgabe/Medienart  E-Book : Dokument : EnglischAlle Ausgaben und Medienarten anzeigen
Zusammenfassung:
Annotation Understanding the molecular basis of bacterial invasion and of host cell adaptation to intracellular bacteria will provide fundamental insights into the pathophysiology of bacteria and the cell biology of the host. This book details specific examples of bacteria that are masters of manipulation of eukaryotic cell signaling and relates these events to the broader context of host-pathogen interaction.  Weiterlesen…
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Gattung/Form: Electronic books
Physisches Format Print version:
Bacterial invasion of host cells.
Cambridge ; New York : Cambridge University Press, 2004
(DLC) 2003053288
Medienart: Dokument, Internetquelle
Dokumenttyp Internet-Ressource, Computerdatei
Alle Autoren: Richard J Lamont
ISBN: 0511187823 9780511187827 0521809541 9780521809542 0511185146 9780511185144 9780511546273 0511546270 9780511186899 0511186894 1107144124 9781107144125 1280457813 9781280457814 9786610457816 6610457816 0511185979 9780511185977 0511313829 9780511313820
OCLC-Nummer: 80246511
Sprachhinweis: English.
Beschreibung: 1 online resource (xiv, 328 pages) : illustrations (some color)
Inhalt: Cover; Half-title; Series-title; Title; Copyright; Contents; Contributors; Preface; Bacterial Invasion of Host Cells; CHAPTER 1 Invasion mechanisms of Salmonella; CLINICAL DESCRIPTION; SALMONELLA ENTRY: SALMONELLA PATHOGENICITY ISLAND-1; The regulation of Salmonella pathogenicity islands; The type III secretion complex; INTERNALIZATION OF SALMONELLA BY THE HOST EPITHELIUM; Animal models of Salmonella infection; Cell culture models of Salmonella infection; INVOLVEMENT OF THE HOST CELL CYTOSKELETON IN BACTERIAL INTERNALIZATION. INVOLVEMENT OF RHO GTPase IN S. TYPHIMURIUM INVASION OF NONPHAGOCYTIC CELLSS. TYPHIMURIUM GENES THAT REGULATE EPITHELIAL CELL INVASION; SopE/SopE2; SopB; SptP; SipC; SipA; ROLE OF SPI-1 IN PATHOGENESIS; HISTORICAL PERSPECTIVE OF SPI-1; REFERENCES; CHAPTER 2 Shigella invasion; INVASION; Shigella invasion and the host inflammatory responses; Basolateral entry into polarized cells; Invasion-associated genes on the large plasmid; Type III secretion system; Secreted effector proteins induce host cellular signaling; IpaA; IpaC; IpgD; VirA; CELL-CELL SPREADING; VirG; VirG ligands; N-WASP; Cdc42. Arp2/3Profilin; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 3 How Yersinia escapes the host: To Yop or not to Yop; THE YERSINIA VIRULENCE SYSTEM; Ysc-Yop III secretion system; Other virulence mechanisms and TTSS present in Yersinia species; FIRST CONTACT; Interaction of the enteropathogenic Y. enterocolitica and Y. pseudotuberculosis with M cells; Y. pestis enters the bloodstream immediately; HOW YERSINIA ESCAPES THE HOST: TO YOP OR NOT TO YOP; Inhibition of phagocytosis; YopE; YopT; YopO/YpkA; YopH; Inhibition of the inflammatory response and induction of apoptosis; YopP/J; YopH. Effectors other than Yops that help to defeat the immune responseYopM; CONCLUSION; REFERENCES; CHAPTER 4 Stealth warfare: The interactions of EPEC and EHEC with host cells; ADHERENCE MECHANISMS REQUIRED FOR INITIAL ATTACHMENT OF EPEC AND EHEC TO HOST CELLS; INTIMATE ATTACHMENT OF EHEC AND EPEC TO HOST CELLS, AND THE TYPE III SECRETORY APPARATUS; HOST CELL RESPONSES TO EHEC AND EPEC INFECTION; Pedestal formation; Inhibition of phagocytosis; Inhibition of mitosis; Disruption of tight junctions; Upregulation of chloride secretion and adenosine triphosphate (ATP) release; The Ca2+ controversy. Activation of mitogen-activated protein (MAP) kinase cascadesModulation of apoptosis; Disruption of mitochondrial membrane potential; Modulation of Cdc42 activity; Modification of host immune responses; Innate immunity; Adaptive immunity; CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 5 Molecular ecology and cell biology of Legionella pneumophila; ECOLOGY OF LEGIONELLAE; ADHERENCE AND ENTRY MECHANISMS; Initial interactions between L. pneumophila and its primitive protozoan hosts; ATTACHMENT AND ENTRY TO MAMMALIAN CELLS; INTRACELLULAR TRAFFICKING.
Serientitel: Advances in molecular and cellular microbiology, 5.
Verfasserangabe: edited by Richard J. Lamont.
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Abstract:

This book addresses an aspect of the processes by which bacteria can cause disease. Specifically, the ability of certain bacteria to gain entry within host cells is described. It is important to  Weiterlesen…

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